Endocannabinoid System


“The endocannabinoid system is intimately involved in tissue healing in the face of inflammatory conditions, correlating clinically with prevention and treatment of inflammation-mediated pain.” – Fine & Rosenfeld, 2013


The Endocannabinoid System

  • CB2 receptors are present in the human dorsal root ganglion (DRG) sensory neurons, mediating nociceptive pain2
  • Cannabinoid receptor agonists modulate nociceptive thresholds.
  • CBD is a positive allosteric modulator at α1 and α 1 β glycine receptors.
  • Influences opioid, 5HT3, and N-methyl-d-aspartate receptors responsible for pain modulation
  • Cannabidiol (CBD)
  • Not psychoactive

This information is presented for educational purposes only. Ananda Hemp developed this information to provide an understanding of the potential applications of cannabinoids. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.