• November 1, 2016

A Brief Primer On Anandamide And The Endocannabinoid System

A Brief Primer On Anandamide And The Endocannabinoid System

A Brief Primer On Anandamide And The Endocannabinoid System 1024 679 Ananda Hemp

A Brief Primer On Anandamide And The Endocannabinoid System

The discovery of CB1 and other cannabinoid receptors in humans, rats and other mammals, along with the discovery of anandamide and related endocannabinoids, opened up a new field of research, while also providing new legitimacy to research into plant-based sources like cannabis and hemp. In the decades since, researchers have come to recognize that cannabinoids play a vital role in human health.

“These molecules are basically produced to help our bodies create balance” noted Ananda Hemp’s John Ryan. “They play vital roles through basically every biological function of our body.”  While initially the first receptors for anandamide and other endocannabinoids were found in the brain, they’ve seen been found in almost every system in the human body. “CB1 receptors are found primarily in the nervous system, connective tissue, gonads, glands, and organs,” noted Michael Jacobs in an introduction to the endocannabinoid system published in November at Ministry of Hemp, a hemp advocacy and information site.

Another cannabinoid receptor, CB2, is found in the immune system and related parts of the body. “By increasing neurogenesis — the formation of new nerve cells — anandamide exhibits both anti-anxiety and antidepressant properties,” reported Deane Alban at Reset.Me in March 2016. “Anandamide, like all neurotransmitters, is fragile and breaks down quickly in the body which is why it doesn’t produce a perpetual state of bliss.” Endocannabinoids are also believed to play an important role in the formation of memories, and research into their action may help unlock the secrets of Alzheimer’s and other diseases that worsen with age. 

CB1, CB2 and other cannabinoid receptors are evolved to respond perfectly to anandamide and other endocannabinoids, which seem to help the body maintain balance in many of its systems. But since plant-based cannabinoids fit into the same chemical “keyholes” in the receptors, humans can use them to pick up the slack when our bodies aren’t producing enough of the natural equivalent.

11 comments
  • ig April 30, 2017 at 8:57 pm

    Highly descriptive post, I enjoyed that a lot. Will there be a
    part 2?

  • Dana @ Ananda Hemp May 5, 2017 at 9:49 pm

    Thanks for the comment! Stay tuned – much more info to come!

  • Tim Fondren May 22, 2017 at 7:14 am

    I’d like to know that prescribed dosage for Amanda hip full spectrum extract 200ū

  • Dana @ Ananda Hemp May 24, 2017 at 6:50 pm

    Hi Tim,

    Thank you for your message! Dosage really depends on each individual and the outcome you are trying to achieve. Send us an email at hello@anandahemp.com. We’d be more than happy to help guide you in the right direction. Thank you!

  • Karen Greb May 25, 2017 at 12:15 am

    A friend gave me some of the softgels to try, they helped joint pain and aided in restful sleep. I think that I may order

  • Dana @ Ananda Hemp May 30, 2017 at 6:59 pm

    Thanks so much for your order Karen! We’d love to hear more feedback once you have been taking them for a bit!

  • Tiffany Vocke July 5, 2017 at 11:30 pm

    Do the capsules have a compounded effect? Meaning will i notice more and more of an improvement the longer amount of time i take them for? I have systemic Lupus. Would taking them daily, even on days I dont have pain, be helpful in reducing overall effects of Lupus, or would i be just as well off only taking them on days I have a lot of pain? Thanks! 🙂

  • Dana @ Ananda Hemp July 6, 2017 at 9:11 pm

    Hi Tiffany! There is little information on the topic but we do believe that a regular intake of cannabinoids will have a compounded effect over time, helping to maintain a state of homeostasis within the system. Cannabinoids influence the immune network. There is data on the impact of exogenous cannabinoids in regards to immune function, which helps us understand how the endocannabinoid system modulates immune phenomena associated with infection or inflammation. Please keep us posted on how the capsules are working for you. You can send us an email anytime at hello@anandahemp.com 🙂

  • POFAW July 20, 2017 at 2:46 am

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  • Tiffany Vocke July 24, 2017 at 8:08 pm

    Thanks, Dana!

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